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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 15,358 European ancestry individuals; replicated in 6,652 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 3 um higher (95% confidence interval 2.27-3.73); p = 7 × 10−16.
How common The G allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 5, band 5q14.3 — in an intron of MIR9-2HG.
What each result means
G/GTwo copies of the version the research linked to Retinal vascular caliber. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Retinal vascular caliber. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Retinal vascular caliber. This is the starting point the study compared everyone against.
PLoS genetics · 2010 · PMID 21060863 · open access
Questions about rs17421627
What is rs17421627?
rs17421627 is a single position in the genome, in or near the MEF2C gene. Published research associates it with retinal vascular caliber. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17421627 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17421627 come from?
GWAS Catalog, PLoS Genet 2010, PMID:21060863. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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