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Retinal vascular caliber

MEF2C · rs17421627

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Retinal vascular caliber compared to the general population. (GWAS Catalog, PLoS Genet 2010, PMID:21060863)

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Retinal vascular caliber. (GWAS Catalog, PLoS Genet 2010, PMID:21060863)

T/T Published research associates this genotype with typical/baseline likelihood of Retinal vascular caliber — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2010, PMID:21060863)

Source: GWAS Catalog, PLoS Genet 2010, PMID:21060863

Questions about rs17421627

What is rs17421627?

rs17421627 is a single position in the genome, in or near the MEF2C gene. Published research associates it with retinal vascular caliber. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17421627 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17421627 come from?

GWAS Catalog, PLoS Genet 2010, PMID:21060863. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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