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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 437,194 European ancestry individuals; replicated in 315,572 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0108 higher (95% confidence interval 0.0075-0.0142); p = 2 × 10−10.
How common The A allele had a frequency of about 98% in the people studied.
Where it sits Chromosome 1, band 1p36.21 — in an intron of DNAJC16.
What each result means
A/ATwo copies of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). This is the starting point the study compared everyone against.
Nature communications · 2021 · PMID 33972514 · open access
Questions about rs17415991
What is rs17415991?
rs17415991 is a single position in the genome, in or near the DNAJC16 gene. Published research associates it with liver enzyme levels (gamma-glutamyl transferase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17415991 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17415991 come from?
GWAS Catalog, Nature communications 2021, PMID:33972514. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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