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Hypo-HDL-cholesterolemia

near LPL · rs17410996

Where this position leads

Condition: Hypo-HDL-Cholesterolemia

rs17410996 Condition: Hypo-HDL-Cholesterolemia Hypo-HDL-Cholesterolemia Condition rs17410996 rs17410996 near LPL

What the study found

Who was studied 14,320 Korean ancestry cases, 36,488 Korean ancestry controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−53.

Where it sits Chromosome 8, band 8p21.3 — between genes, 24.5 kb from LPL.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Hypo-HDL-cholesterolemia — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hypo-HDL-cholesterolemia.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hypo-HDL-cholesterolemia compared to the general population.
Source
Lifestage Sex-Specific Genetic Effects on Metabolic Disorders in an Adult Population in Korea: The Korean Genome and Epidemiology Study
Kim YS, Park YC, Choi JE, Park JM, Han K, Kim K, Kim BT, Hong KW
International journal of molecular sciences · 2022 · PMID 36233190 · open access

Questions about rs17410996

What is rs17410996?

rs17410996 is a single position in the genome, in or near the near LPL gene. Published research associates it with hypo-hdl-cholesterolemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17410996 linked to?

On MyGeneLog this position is linked to Hypo-HDL-Cholesterolemia. The research behind each link, and its sources, are set out on that condition page.

Does having rs17410996 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17410996 come from?

GWAS Catalog, International journal of molecular sciences 2022, PMID:36233190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hypo-HDL-cholesterolemia (rs17410996). MyGeneLog™. https://www.mygenelog.com/variants/rs17410996

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