Sensitive

Hepatocellular carcinoma

UBE4B · rs17401966

Where this position leads

Condition: HBV-Related Hepatocellular Carcinoma

rs17401966 Condition: HBV-Related Hepatocellular Carcinoma HBV-Related Hepatocellular Carcinoma Condition Topic: Infection and immunity Infection and immunity Topic rs17401966 rs17401966 UBE4B

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 348 Chinese ancestry cases, 359 Chinese ancestry controls; replicated in 2,121 Chinese ancestry cases, 1,748 Chinese ancestry controls.

The effect Each copy of the A allele carried 1.64 times the odds of Hepatocellular carcinoma (95% confidence interval 1.49-1.82); p = 2 × 10−18.

How common The A allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 1, band 1p36.22 — in an intron of KIF1B.

What each result means

A/A Two copies of the version the research linked to Hepatocellular carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Hepatocellular carcinoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Hepatocellular carcinoma. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs17401966

What is rs17401966?

rs17401966 is a single position in the genome, in or near the UBE4B gene. Published research associates it with hepatocellular carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17401966 linked to?

On MyGeneLog this position is linked to HBV-Related Hepatocellular Carcinoma. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs17401966?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (11 papers), alcohol and the flush (1 papers), liver (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs17401966 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17401966 come from?

GWAS Catalog, Nat Genet 2010, PMID:20676096. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hepatocellular carcinoma (rs17401966). MyGeneLog™. https://www.mygenelog.com/variants/rs17401966

← See all variants