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Brainstem global volume Medulla

HEY2-AS1 · rs1739358

What the study found

Who was studied 21,282 British ancestry individuals; replicated in 10,686 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.068 higher (95% confidence interval 0.048-0.088); p = 5 × 10−12.

How common The A allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 6, band 6q22.31 — in an intron of HEY2-AS1.

What each result means

A/A Two copies of the version the research linked to Brainstem global volume Medulla. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Brainstem global volume Medulla. That is a smaller link than two copies.
G/G No copy of the version the research linked to Brainstem global volume Medulla. This is the starting point the study compared everyone against.
Source

Questions about rs1739358

What is rs1739358?

rs1739358 is a single position in the genome, in or near the HEY2-AS1 gene. Published research associates it with brainstem global volume medulla. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1739358 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1739358 come from?

GWAS Catalog, Nature neuroscience 2021, PMID:33875891. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Brainstem global volume Medulla (rs1739358). MyGeneLog™. https://www.mygenelog.com/variants/rs1739358

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