FAF1 · rs17384696
Where this position leads
Condition: Headache
Strength of the evidence
Its strongest genetic-study result is p = 10−9, with 1 associations in the GWAS Catalog.
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 84,036 European ancestry headache cases, 335,552 European ancestry controls without headache, 366,759 European ancestry indviduals with glucose.
The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−9.
Where it sits Chromosome 1, band 1p32.3 — in an intron of FAF1.
rs17384696 is a single position in the genome, in or near the FAF1 gene. Published research associates it with headache or glucose levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Headache. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Human genetics 2023, PMID:36808568. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Headache or glucose levels (rs17384696). MyGeneLog™. https://www.mygenelog.com/variants/rs17384696