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Diabetic retinopathy

KIAA0825 · rs17376456

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diabetic retinopathy compared to the general population. (GWAS Catalog, Ophthalmology 2011, PMID:21310492)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diabetic retinopathy. (GWAS Catalog, Ophthalmology 2011, PMID:21310492)

G/G Published research associates this genotype with typical/baseline likelihood of Diabetic retinopathy — no copies of the reported risk allele. (GWAS Catalog, Ophthalmology 2011, PMID:21310492)

Source: GWAS Catalog, Ophthalmology 2011, PMID:21310492

Questions about rs17376456

What is rs17376456?

rs17376456 is a single position in the genome, in or near the KIAA0825 gene. Published research associates it with diabetic retinopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17376456 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17376456 come from?

GWAS Catalog, Ophthalmology 2011, PMID:21310492. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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