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Who was studied 34,433 European ancestry individuals; replicated in Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.85 mm Hg lower (95% confidence interval 0.63-1.07); p = 2 × 10−13.
How common The G allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 1, band 1p36.22 — in an intron of MTHFR.
What ClinVar records
ClassificationBenign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2018-07-27.
ClinVar record 1237104NM_005957.5(MTHFR):c.236+160T>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ANo copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs17367504
What is rs17367504?
rs17367504 is a single position in the genome, in or near the NPPA gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17367504 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs17367504?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), caffeine and energy drinks (1 papers), depression and stress (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs17367504 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17367504 come from?
GWAS Catalog, Nat Genet 2009, PMID:19430483. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 502218122230Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others30Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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