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Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 22,161 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.26 higher (95% confidence interval 0.20-0.32); p = 5 × 10−16.
Where it sits Chromosome 16, band 16q13 — between genes, 7.6 kb from LOC124903811.
What each result means
C/CTwo copies of the version the research linked to HDL Cholesterol - Triglycerides (HDLC-TG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to HDL Cholesterol - Triglycerides (HDLC-TG). That is a smaller link than two copies.
T/TNo copy of the version the research linked to HDL Cholesterol - Triglycerides (HDLC-TG). This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs173539
What is rs173539?
rs173539 is a single position in the genome, in or near the CETP gene. Published research associates it with hdl cholesterol - triglycerides (hdlc-tg). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs173539 linked to?
On MyGeneLog this position is linked to Metabolic Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does rs173539 affect how medicines work?
CETP carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
What do people read about alongside rs173539?
Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (3 papers), blood sugar and insulin (1 papers), cholesterol and blood fats (1 papers), infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs173539 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs173539 come from?
GWAS Catalog, Diabetes 2011, PMID:21386085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 5353144122229Reads by AI crawlersClaude5ChatGPT3Google · Gemini1Perplexity4Meta AI4Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total53Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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