Standard

Tryptophan levels

TDO2 · rs17314234

What the study found

Who was studied 30,974 Caucasian ancestry individuals.

The effect Each copy of the C allele shifted the measure 12.9 (zscore) higher; p = 3 × 10−38.

How common The C allele had a frequency of about 90% in the people studied.

Where it sits Chromosome 4, band 4q32.1 — inside TDO2.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Tryptophan levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Tryptophan levels.
T/T Published research associates this genotype with typical/baseline likelihood of Tryptophan levels — no copies of the reported risk allele.
Source

Questions about rs17314234

What is rs17314234?

rs17314234 is a single position in the genome, in or near the TDO2 gene. Published research associates it with tryptophan levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17314234 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17314234 come from?

GWAS Catalog, Nature genetics 2021, PMID:33414548. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Tryptophan levels (rs17314234). MyGeneLog™. https://www.mygenelog.com/variants/rs17314234

← See all variants