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Serum alkaline phosphatase levels

GPLD1 · rs17300770

What the study found

Who was studied 162,774 Icelandic ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.09 lower (95% confidence interval 0.10-0.08); p = 3 × 10−43.

How common The C allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — a missense change in GPLD1.

What each result means

C/C Two copies of the version the research linked to Serum alkaline phosphatase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Serum alkaline phosphatase levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum alkaline phosphatase levels. This is the starting point the study compared everyone against.
Source

Questions about rs17300770

What is rs17300770?

rs17300770 is a single position in the genome, in or near the GPLD1 gene. Published research associates it with serum alkaline phosphatase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17300770 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17300770 come from?

GWAS Catalog, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020, PMID:31666285. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Serum alkaline phosphatase levels (rs17300770). MyGeneLog™. https://www.mygenelog.com/variants/rs17300770

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