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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 15,197 White ancestry cases, 223,207 White ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.00522 higher; p = 4 × 10−11.
Where it sits Chromosome 16, band 16q12.1 — in an intron of TOX3.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hormone-sensitive cancer compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hormone-sensitive cancer.
T/TPublished research associates this genotype with typical/baseline likelihood of Hormone-sensitive cancer — no copies of the reported risk allele.
Communications biology · 2022 · PMID 35729236 · open access
Questions about rs17271951
What is rs17271951?
rs17271951 is a single position in the genome, in or near the TOX3 gene. Published research associates it with hormone-sensitive cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17271951 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17271951 come from?
GWAS Catalog, Communications biology 2022, PMID:35729236. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Hormone-sensitive cancer (rs17271951). MyGeneLog™. https://www.mygenelog.com/variants/rs17271951