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acne vulgaris

CSTA · rs17265703

What the study found

Who was studied 20,165 European ancestry cases, 595,231 European ancestry controls.

The effect Each copy of the G allele carried 1.13 times the odds of acne vulgaris (95% confidence interval 1.09–1.17); p = 2 × 10−13.

How common The G allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 3, band 3q21.1 — in an intron of CSTA.

What each result means

A/A No copy of the version the research linked to acne vulgaris. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to acne vulgaris. That is a smaller link than two copies.
G/G Two copies of the version the research linked to acne vulgaris. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17265703

What is rs17265703?

rs17265703 is a single position in the genome, in or near the CSTA gene. Published research associates it with acne vulgaris. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17265703 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17265703 come from?

GWAS Catalog, Nature communications 2022, PMID:35132056. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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acne vulgaris (rs17265703). MyGeneLog™. https://www.mygenelog.com/variants/rs17265703

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