Sensitive

Serum metabolite concentrations in chronic kidney disease

CDH18 · rs17253658

Where this position leads

Condition: Serum Metabolites in Chronic Kidney Disease

rs17253658 Condition: Serum Metabolites in Chronic Kidney Disease Serum Metabolites in Chronic Kidney… Condition rs17253658 rs17253658 CDH18

What the study found

Who was studied 1,143 European ancestry cases.

The effect Each copy of the T allele shifted the measure 0.476 higher (95% confidence interval 0.31-0.64); p = 1 × 10−8.

Where it sits Chromosome 5, band 5p14.3 — inside LOC102723561.

What each result means

C/C No copy of the version the research linked to Serum metabolite concentrations in chronic kidney disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Serum metabolite concentrations in chronic kidney disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Serum metabolite concentrations in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17253658

What is rs17253658?

rs17253658 is a single position in the genome, in or near the CDH18 gene. Published research associates it with serum metabolite concentrations in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17253658 linked to?

On MyGeneLog this position is linked to Serum Metabolites in Chronic Kidney Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs17253658 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17253658 come from?

GWAS Catalog, J Am Soc Nephrol 2018, PMID:29545352. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum metabolite concentrations in chronic kidney disease (rs17253658). MyGeneLog™. https://www.mygenelog.com/variants/rs17253658

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