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Blood pressure

ATP2B1 · rs17249754

Where this position leads

Condition: Blood Pressure

rs17249754 Condition: Blood Pressure Blood Pressure Condition rs17249754 rs17249754 ATP2B1

What the study found

Who was studied 19,608 East Asian ancestry individuals; replicated in 30,765 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 1.17 mm Hg higher (95% confidence interval 0.92-1.42); p = 8 × 10−20.

How common The G allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 12, band 12q21.33 — in an intron of ATP2B1.

What each result means

A/A No copy of the version the research linked to Blood pressure. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Blood pressure. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs17249754

What is rs17249754?

rs17249754 is a single position in the genome, in or near the ATP2B1 gene. Published research associates it with blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17249754 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs17249754?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (2 papers), blood sugar and insulin (1 papers), alcohol and the flush (1 papers), exercise and muscle (1 papers), bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs17249754 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17249754 come from?

GWAS Catalog, Nat Genet 2011, PMID:21572416. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blood pressure (rs17249754). MyGeneLog™. https://www.mygenelog.com/variants/rs17249754

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