Standard

Blond vs. brown/black hair color

LOC105378966 · rs17248377

Where this position leads

Condition: Hair Color

rs17248377 Condition: Hair Color Hair Color Condition rs17248377 rs17248377 LOC105378966

What the study found

Who was studied 39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−11.

How common The A allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 5, band 5q11.2 — between genes, 0.6 kb from LINC02105.

What each result means

A/A Two copies of the version the research linked to Blond vs. brown/black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Blond vs. brown/black hair color. That is a smaller link than two copies.
G/G No copy of the version the research linked to Blond vs. brown/black hair color. This is the starting point the study compared everyone against.
Source

Questions about rs17248377

What is rs17248377?

rs17248377 is a single position in the genome, in or near the LOC105378966 gene. Published research associates it with blond vs. brown/black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17248377 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs17248377 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17248377 come from?

GWAS Catalog, Nature communications 2018, PMID:30531825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blond vs. brown/black hair color (rs17248377). MyGeneLog™. https://www.mygenelog.com/variants/rs17248377

← See all variants