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Pit-and-Fissure caries

KPNA4 · rs17236529

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Pit-and-Fissure caries — no copies of the reported risk allele. (GWAS Catalog, Caries Res 2014, PMID:24556642)

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pit-and-Fissure caries. (GWAS Catalog, Caries Res 2014, PMID:24556642)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pit-and-Fissure caries compared to the general population. (GWAS Catalog, Caries Res 2014, PMID:24556642)

Source: GWAS Catalog, Caries Res 2014, PMID:24556642

Questions about rs17236529

What is rs17236529?

rs17236529 is a single position in the genome, in or near the KPNA4 gene. Published research associates it with pit-and-fissure caries. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17236529 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17236529 come from?

GWAS Catalog, Caries Res 2014, PMID:24556642. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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