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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 684,122 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.022 higher; p = 1 × 10−12.
Where it sits Chromosome 21, band 21q22.12 — in a regulatory region of RUNX1.
What each result means
C/CTwo copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
Communications biology · 2020 · PMID 32327693 · open access
Questions about rs17227231
What is rs17227231?
rs17227231 is a single position in the genome, in or near the RUNX1 gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17227231 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17227231 come from?
GWAS Catalog, Communications biology 2020, PMID:32327693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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