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Blond vs. brown/black hair color

MSH5 · rs17207524

Where this position leads

Condition: Hair Color

rs17207524 Condition: Hair Color Hair Color Condition rs17207524 rs17207524 MSH5

What the study found

Who was studied 39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 3 × 10−8.

How common The T allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — in an intron of MSH5.

What each result means

G/G No copy of the version the research linked to Blond vs. brown/black hair color. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Blond vs. brown/black hair color. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Blond vs. brown/black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17207524

What is rs17207524?

rs17207524 is a single position in the genome, in or near the MSH5 gene. Published research associates it with blond vs. brown/black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17207524 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs17207524 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17207524 come from?

GWAS Catalog, Nature communications 2018, PMID:30531825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blond vs. brown/black hair color (rs17207524). MyGeneLog™. https://www.mygenelog.com/variants/rs17207524

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