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Lymphocyte-to-monocyte ratio

near HLA-C · rs17192134

What the study found

Who was studied 234,184 European ancestry individuals; replicated in 100,284 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 3 × 10−52.

How common The G allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 6.5 kb from HLA-C.

What each result means

G/G Two copies of the version the research linked to Lymphocyte-to-monocyte ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Lymphocyte-to-monocyte ratio. That is a smaller link than two copies.
T/T No copy of the version the research linked to Lymphocyte-to-monocyte ratio. This is the starting point the study compared everyone against.
Source

Questions about rs17192134

What is rs17192134?

rs17192134 is a single position in the genome, in or near the near HLA-C gene. Published research associates it with lymphocyte-to-monocyte ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17192134 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17192134 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lymphocyte-to-monocyte ratio (rs17192134). MyGeneLog™. https://www.mygenelog.com/variants/rs17192134

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