Standard
White blood cell count (basophil)
FAM46A · rs171835
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of White blood cell count (basophil) compared to the general population. (GWAS Catalog, Cell 2016, PMID:27863252)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with White blood cell count (basophil). (GWAS Catalog, Cell 2016, PMID:27863252)
G/G
Published research associates this genotype with typical/baseline likelihood of White blood cell count (basophil) — no copies of the reported risk allele. (GWAS Catalog, Cell 2016, PMID:27863252)
Source
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
Astle WJ,
Elding H,
Jiang T,
Allen D,
Ruklisa D,
Mann AL,
Mead D,
Bouman H,
Riveros-Mckay F,
Kostadima MA,
Lambourne JJ,
Sivapalaratnam S
and 62 more — show all
Downes K,
Kundu K,
Bomba L,
Berentsen K,
Bradley JR,
Daugherty LC,
Delaneau O,
Freson K,
Garner SF,
Grassi L,
Guerrero J,
Haimel M,
Janssen-Megens EM,
Kaan A,
Kamat M,
Kim B,
Mandoli A,
Marchini J,
Martens JHA,
Meacham S,
Megy K,
O'Connell J,
Petersen R,
Sharifi N,
Sheard SM,
Staley JR,
Tuna S,
van der Ent M,
Walter K,
Wang SY,
Wheeler E,
Wilder SP,
Iotchkova V,
Moore C,
Sambrook J,
Stunnenberg HG,
Di Angelantonio E,
Kaptoge S,
Kuijpers TW,
Carrillo-de-Santa-Pau E,
Juan D,
Rico D,
Valencia A,
Chen L,
Ge B,
Vasquez L,
Kwan T,
Garrido-Martín D,
Watt S,
Yang Y,
Guigo R,
Beck S,
Paul DS,
Pastinen T,
Bujold D,
Bourque G,
Frontini M,
Danesh J,
Roberts DJ,
Ouwehand WH,
Butterworth AS,
Soranzo N
Cell · 2016 · PMID 27863252 · open access
Questions about rs171835
What is rs171835?
rs171835 is a single position in the genome, in or near the FAM46A gene. Published research associates it with white blood cell count (basophil). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs171835 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs171835 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants