Standard
Refractive error
MYO1D · rs17183295
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Refractive error — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Refractive error.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Refractive error compared to the general population.
Source
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
Verhoeven VJ,
Hysi PG,
Wojciechowski R,
Fan Q,
Guggenheim JA,
Höhn R,
MacGregor S,
Hewitt AW,
Nag A,
Cheng CY,
Yonova-Doing E,
Zhou X
and 96 more — show all
Ikram MK,
Buitendijk GH,
McMahon G,
Kemp JP,
Pourcain BS,
Simpson CL,
Mäkelä KM,
Lehtimäki T,
Kähönen M,
Paterson AD,
Hosseini SM,
Wong HS,
Xu L,
Jonas JB,
Pärssinen O,
Wedenoja J,
Yip SP,
Ho DW,
Pang CP,
Chen LJ,
Burdon KP,
Craig JE,
Klein BE,
Klein R,
Haller T,
Metspalu A,
Khor CC,
Tai ES,
Aung T,
Vithana E,
Tay WT,
Barathi VA,
Chen P,
Li R,
Liao J,
Zheng Y,
Ong RT,
Döring A,
Evans DM,
Timpson NJ,
Verkerk AJ,
Meitinger T,
Raitakari O,
Hawthorne F,
Spector TD,
Karssen LC,
Pirastu M,
Murgia F,
Ang W,
Mishra A,
Montgomery GW,
Pennell CE,
Cumberland PM,
Cotlarciuc I,
Mitchell P,
Wang JJ,
Schache M,
Janmahasatian S,
Igo RP Jr,
Lass JH,
Chew E,
Iyengar SK,
Gorgels TG,
Rudan I,
Hayward C,
Wright AF,
Polasek O,
Vatavuk Z,
Wilson JF,
Fleck B,
Zeller T,
Mirshahi A,
Müller C,
Uitterlinden AG,
Rivadeneira F,
Vingerling JR,
Hofman A,
Oostra BA,
Amin N,
Bergen AA,
Teo YY,
Rahi JS,
Vitart V,
Williams C,
Baird PN,
Wong TY,
Oexle K,
Pfeiffer N,
Mackey DA,
Young TL,
van Duijn CM,
Saw SM,
Bailey-Wilson JE,
Stambolian D,
Klaver CC,
Hammond CJ
Nature genetics · 2013 · PMID 23396134
Questions about rs17183295
What is rs17183295?
rs17183295 is a single position in the genome, in or near the MYO1D gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17183295 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17183295 come from?
GWAS Catalog, Nat Genet 2013, PMID:23396134. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants