Standard

Total hippocampal volume

WIF1 · rs17178139

What the study found

Who was studied 21,297 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 58.1 mm3 lower; p = 2 × 10−20.

Where it sits Chromosome 12, band 12q14.3 — in an intron of MSRB3.

What each result means

A/A Two copies of the version the research linked to Total hippocampal volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Total hippocampal volume. That is a smaller link than two copies.
G/G No copy of the version the research linked to Total hippocampal volume. This is the starting point the study compared everyone against.
Source

Questions about rs17178139

What is rs17178139?

rs17178139 is a single position in the genome, in or near the WIF1 gene. Published research associates it with total hippocampal volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17178139 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17178139 come from?

GWAS Catalog, Mol Psychiatry 2018, PMID:30279459. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total hippocampal volume (rs17178139). MyGeneLog™. https://www.mygenelog.com/variants/rs17178139

← See all variants