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Neonatal cytokine/chemokine levels (maternal genetic effect)

EFNA5 · rs17159338

What the study found

Who was studied 790 Hispanic, European, Asian, South Asian or African American individuals.

The effect Each copy of the C allele shifted the measure 0.36 lower (95% confidence interval 0.24-0.48); p = 1 × 10−9.

How common The C allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 5, band 5q21.3 — in an intron of LINC01950.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Neonatal cytokine/chemokine levels (maternal genetic effect) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Neonatal cytokine/chemokine levels (maternal genetic effect).
T/T Published research associates this genotype with typical/baseline likelihood of Neonatal cytokine/chemokine levels (maternal genetic effect) — no copies of the reported risk allele.
Source

Questions about rs17159338

What is rs17159338?

rs17159338 is a single position in the genome, in or near the EFNA5 gene. Published research associates it with neonatal cytokine/chemokine levels (maternal genetic effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17159338 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17159338 come from?

GWAS Catalog, Genome Med 2018, PMID:30134952. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neonatal cytokine/chemokine levels (maternal genetic effect) (rs17159338). MyGeneLog™. https://www.mygenelog.com/variants/rs17159338

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