Standard

Urinary albumin excretion

WIPF3 · rs17158386

Where this position leads

Condition: Kidney Function

rs17158386 Condition: Kidney Function Kidney Function Condition rs17158386 rs17158386 WIPF3

What the study found

Who was studied 382,500 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0133 higher (95% confidence interval 0.0096-0.017); p = 4 × 10−12.

How common The A allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 7, band 7p14.3 — between genes, 23.1 kb from DPY19L2P3.

What each result means

A/A Two copies of the version the research linked to Urinary albumin excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Urinary albumin excretion. That is a smaller link than two copies.
G/G No copy of the version the research linked to Urinary albumin excretion. This is the starting point the study compared everyone against.
Source

Questions about rs17158386

What is rs17158386?

rs17158386 is a single position in the genome, in or near the WIPF3 gene. Published research associates it with urinary albumin excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17158386 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs17158386 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17158386 come from?

GWAS Catalog, Am J Hum Genet 2018, PMID:30220432. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary albumin excretion (rs17158386). MyGeneLog™. https://www.mygenelog.com/variants/rs17158386

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