Standard

Creatinine levels

GRB10 · rs17152083

Where this position leads

Condition: Kidney Function

rs17152083 Condition: Kidney Function Kidney Function Condition rs17152083 rs17152083 GRB10

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the C allele shifted the measure 0.02 mmol/L higher (95% confidence interval 0.02-0.02); p = 3 × 10−11.

Where it sits Chromosome 7, band 7p12.1 — in an intron of GRB10.

What each result means

C/C Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs17152083

What is rs17152083?

rs17152083 is a single position in the genome, in or near the GRB10 gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17152083 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs17152083 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17152083 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine levels (rs17152083). MyGeneLog™. https://www.mygenelog.com/variants/rs17152083

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