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Who was studied 1,138 European ancestry cases, 1,120 European ancestry normal or lean controls; replicated in 1,181 European ancestry cases, 1,960 European ancestry normal or lean controls, 981 European ancestry cases and 1,430 European ancestry controls from 715 families.
The effect
Each copy of the A allele carried 1.18 times the odds of Obesity (early onset extreme) (95% confidence interval 1.03-1.35); p = 2 × 10−8.
Where it sits Chromosome 8, band 8p23.1 — inside LOC124902056.
What each result means
A/ATwo copies of the version the research linked to Obesity (early onset extreme). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Obesity (early onset extreme). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Obesity (early onset extreme). This is the starting point the study compared everyone against.
PLoS genetics · 2010 · PMID 20421936 · open access
Questions about rs17150703
What is rs17150703?
rs17150703 is a single position in the genome, in or near the MSRA gene. Published research associates it with obesity (early onset extreme). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17150703 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs17150703 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17150703 come from?
GWAS Catalog, PLoS Genet 2010, PMID:20421936. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 4132727223310Reads by AI crawlersClaude3ChatGPT2Google · Gemini7Perplexity2Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others10Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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