Standard
Vertical cup-disc ratio
SCYL1 · rs17146964
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Vertical cup-disc ratio — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Vertical cup-disc ratio.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Vertical cup-disc ratio compared to the general population.
Source
A genome-wide association study of optic disc parameters
Ramdas WD,
van Koolwijk LM,
Ikram MK,
Jansonius NM,
de Jong PT,
Bergen AA,
Isaacs A,
Amin N,
Aulchenko YS,
Wolfs RC,
Hofman A,
Rivadeneira F
and 8 more — show all
PLoS genetics · 2010 · PMID 20548946 · open access
Questions about rs17146964
What is rs17146964?
rs17146964 is a single position in the genome, in or near the SCYL1 gene. Published research associates it with vertical cup-disc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17146964 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17146964 come from?
GWAS Catalog, PLoS Genet 2010, PMID:20548946. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants