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Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 2,758 European ancestry individuals; replicated in 18,554 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.14 lower (95% confidence interval 0.25-0.53); p = 7 × 10−22.
How common The T allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 7, band 7q11.23 — in the 3′ untranslated region of TBL2.
What each result means
C/CNo copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs17145738
What is rs17145738?
rs17145738 is a single position in the genome, in or near the TBL2 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17145738 linked to?
On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs17145738?
Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (3 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs17145738 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17145738 come from?
GWAS Catalog, Nat Genet 2008, PMID:18193044. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 473246122126Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity4Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others26Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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