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Who was studied 10,792 European ancestry male cases, 190,694 European ancestry male controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 1 × 10−20.
Where it sits Chromosome 12, band 12q13.13 — in an intron of KRT8.
What each result means
C/CNo copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2020 · PMID 32887889 · open access
Questions about rs17120257
What is rs17120257?
rs17120257 is a single position in the genome, in or near the KRT8 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17120257 linked to?
On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs17120257 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17120257 come from?
GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 152319Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Prostate cancer (rs17120257). MyGeneLog™. https://www.mygenelog.com/variants/rs17120257