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Corneal curvature

CMPK1 · rs17103186

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 3,178 Chinese ancestry individuals, 2,138 Malay ancestry individuals, 2,124 Asian Indian ancestry individuals; replicated in 2,473 Chinese ancestry individuals, 2,747 Japanese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.11 higher (95% confidence interval 0.071-0.149); p = 3 × 10⁻¹².

How common The C allele had a frequency of about 82% in the people studied.

Where it sits Chromosome 1, band 1p33 — in an intron of LINC01389.

What each result means

C/C Two copies of the version the research linked to Corneal curvature. That is the strongest link of the three results. A link in a study is not a diagnosis.

C/T One copy of the version the research linked to Corneal curvature. That is a smaller link than two copies.

T/T No copy of the version the research linked to Corneal curvature. This is the starting point the study compared everyone against.

Source

CMPK1 and RBP3 are associated with corneal curvature in Asian populations

Chen P, Miyake M, Fan Q, Liao J, Yamashiro K, Ikram MK, Chew M, Vithana EN, Khor CC, Aung T, Tai ES, Wong TY

and 4 more — show all

Teo YY, Yoshimura N, Saw SM, Cheng CY

Human molecular genetics · 2014 · PMID 24963161

What people read about alongside this

Short-sightedness and screens2

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs17103186

What is rs17103186?

rs17103186 is a single position in the genome, in or near the CMPK1 gene. Published research associates it with corneal curvature. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs17103186?

Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs17103186 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17103186 come from?

GWAS Catalog, Hum Mol Genet 2014, PMID:24963161. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Corneal curvature (rs17103186). MyGeneLog™. https://www.mygenelog.com/variants/rs17103186

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