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Ankylosing spondylitis

ANO6 · rs17095830

Where this position leads

Condition: Ankylosing Spondylitis

rs17095830 Condition: Ankylosing Spondylitis Ankylosing Spondylitis Condition rs17095830 rs17095830 ANO6

What the study found

Who was studied 1,837 Han Chinese ancestry cases, 4,231 Han Chinese ancestry controls; replicated in 2,100 Han Chinese ancestry cases, 3,496 Han Chinese ancestry controls.

The effect Each copy of the G allele carried 1.29 times the odds of Ankylosing spondylitis (95% confidence interval 1.18-1.41); p = 2 × 10−8.

How common The G allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 12, band 12q12 — in an intron of ANO6.

What each result means

A/A No copy of the version the research linked to Ankylosing spondylitis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Ankylosing spondylitis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Ankylosing spondylitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17095830

What is rs17095830?

rs17095830 is a single position in the genome, in or near the ANO6 gene. Published research associates it with ankylosing spondylitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17095830 linked to?

On MyGeneLog this position is linked to Ankylosing Spondylitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs17095830 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17095830 come from?

GWAS Catalog, Nat Genet 2011, PMID:22138694. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ankylosing spondylitis (rs17095830). MyGeneLog™. https://www.mygenelog.com/variants/rs17095830

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