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Biliary atresia

XPNPEP1 · rs17095355

Where this position leads

Condition: Biliary Atresia

rs17095355 Condition: Biliary Atresia Biliary Atresia Condition rs17095355 rs17095355 XPNPEP1

What the study found

Who was studied 281 Chinese ancestry cases, 481 Chinese ancestry controls; replicated in 124 Chinese ancestry cases, 90 Chinese ancestry controls.

The effect Each copy of the T allele carried 1.77 times the odds of Biliary atresia (95% confidence interval 1.38-2.26); p = 7 × 10−9.

How common The T allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 10, band 10q25.1 — in an intron of ADD3-AS1.

What each result means

C/C No copy of the version the research linked to Biliary atresia. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Biliary atresia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Biliary atresia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs17095355

What is rs17095355?

rs17095355 is a single position in the genome, in or near the XPNPEP1 gene. Published research associates it with biliary atresia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17095355 linked to?

On MyGeneLog this position is linked to Biliary Atresia. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs17095355?

Subjects that appear in the title or abstract of the same papers as this rsID include liver (1 papers), natural selection (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs17095355 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17095355 come from?

GWAS Catalog, Hum Mol Genet 2010, PMID:20460270. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Biliary atresia (rs17095355). MyGeneLog™. https://www.mygenelog.com/variants/rs17095355

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