Sensitive
Anxiety disorder
LOC152225 · rs1709393
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Anxiety disorder compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Anxiety disorder.
T/T
Published research associates this genotype with typical/baseline likelihood of Anxiety disorder — no copies of the reported risk allele.
Source
Meta-analysis of genome-wide association studies of anxiety disorders
Otowa T,
Hek K,
Lee M,
Byrne EM,
Mirza SS,
Nivard MG,
Bigdeli T,
Aggen SH,
Adkins D,
Wolen A,
Fanous A,
Keller MC
and 35 more — show all
Castelao E,
Kutalik Z,
Van der Auwera S,
Homuth G,
Nauck M,
Teumer A,
Milaneschi Y,
Hottenga JJ,
Direk N,
Hofman A,
Uitterlinden A,
Mulder CL,
Henders AK,
Medland SE,
Gordon S,
Heath AC,
Madden PA,
Pergadia ML,
van der Most PJ,
Nolte IM,
van Oort FV,
Hartman CA,
Oldehinkel AJ,
Preisig M,
Grabe HJ,
Middeldorp CM,
Penninx BW,
Boomsma D,
Martin NG,
Montgomery G,
Maher BS,
van den Oord EJ,
Wray NR,
Tiemeier H,
Hettema JM
Molecular psychiatry · 2016 · PMID 26754954 · open access
Questions about rs1709393
What is rs1709393?
rs1709393 is a single position in the genome, in or near the LOC152225 gene. Published research associates it with anxiety disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1709393 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1709393 come from?
GWAS Catalog, Mol Psychiatry 2016, PMID:26754954. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants