KLF12 · rs17090300
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 330 Chinese ancestry left-side-affected cases, 609 Chinese ancestry right-side-affected cases, 2,012 Chinese ancestry controls; replicated in 151 Chinese ancestry left-side-affected cases, 292 Chinese ancestry right-side-affected cases, 1,669 Chinese ancestry controls.
The effect Each copy of the G allele carried 2.31 times the odds of Craniofacial microsomia (95% confidence interval 1.81-2.93); p = 1 × 10−11.
How common The G allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 13, band 13q22.1 — in an intron of LINC00392.
rs17090300 is a single position in the genome, in or near the KLF12 gene. Published research associates it with craniofacial microsomia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2016, PMID:26853712. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Craniofacial microsomia (rs17090300). MyGeneLog™. https://www.mygenelog.com/variants/rs17090300