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Spherical equivalent

TENM3 · rs17074027

What the study found

Who was studied 1,237 Southern Han Chinese ancestry individuals; replicated in 4,093 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.36 lower; p = 8 × 10−11.

Where it sits Chromosome 4, band 4q35.1 — in an intron of TENM3.

What each result means

G/G Two copies of the version the research linked to Spherical equivalent. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Spherical equivalent. That is a smaller link than two copies.
T/T No copy of the version the research linked to Spherical equivalent. This is the starting point the study compared everyone against.
Source

Questions about rs17074027

What is rs17074027?

rs17074027 is a single position in the genome, in or near the TENM3 gene. Published research associates it with spherical equivalent. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17074027 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17074027 come from?

GWAS Catalog, NPJ genomic medicine 2025, PMID:40410244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Spherical equivalent (rs17074027). MyGeneLog™. https://www.mygenelog.com/variants/rs17074027

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