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Neuroblastoma

LIN28B · rs17065417

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Neuroblastoma compared to the general population. (GWAS Catalog, Nat Genet 2012, PMID:22941191)

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Neuroblastoma. (GWAS Catalog, Nat Genet 2012, PMID:22941191)

C/C Published research associates this genotype with typical/baseline likelihood of Neuroblastoma — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2012, PMID:22941191)

Source

Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma

Diskin SJ, Capasso M, Schnepp RW, Cole KA, Attiyeh EF, Hou C, Diamond M, Carpenter EL, Winter C, Lee H, Jagannathan J, Latorre V

and 4 more — show all

Iolascon A, Hakonarson H, Devoto M, Maris JM

Nature genetics · 2012 · PMID 22941191 · open access

Questions about rs17065417

What is rs17065417?

rs17065417 is a single position in the genome, in or near the LIN28B gene. Published research associates it with neuroblastoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17065417 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17065417 come from?

GWAS Catalog, Nat Genet 2012, PMID:22941191. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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