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Self-reported endometriosis

KCTD9 · rs17053711

Where this position leads

What the study found

Who was studied 50,867 European ancestry cases, 528,391 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0211 lower (95% confidence interval 0.014-0.028); p = 1 × 10⁻⁸.

How common The A allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 8, band 8p21.2 — in an intron of KCTD9.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Self-reported endometriosis compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Self-reported endometriosis.

G/G Published research associates this genotype with typical/baseline likelihood of Self-reported endometriosis — no copies of the reported risk allele.

Source

Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations

Koller D, He J, Løkhammer S, Aranda S, Qiu D, Davtian D, Chen Q, Xu Z, Mao Z, Friligkou E, Karaca S, Cormand B

and 5 more — show all

Flores I, Altmäe S, Mitjans M, Cabrera-Mendoza B, Polimanti R

Nature genetics · 2026 · PMID 42056605

Questions about rs17053711

What is rs17053711?

rs17053711 is a single position in the genome, in or near the KCTD9 gene. Published research associates it with self-reported endometriosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17053711 linked to?

On MyGeneLog this position is linked to Endometriosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs17053711 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17053711 come from?

GWAS Catalog, Nature genetics 2026, PMID:42056605. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Self-reported endometriosis (rs17053711). MyGeneLog™. https://www.mygenelog.com/variants/rs17053711

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