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Well-being spectrum (multivariate analysis)

near FANCL · rs17049478

What the study found

Who was studied 2,083,151 European ancestry individuals; replicated in 287,239 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0101 higher (95% confidence interval 0.0066-0.0135); p = 1 × 10−8.

How common The A allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 2, band 2p16.1 — between genes, 56.1 kb from LINC01795.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Well-being spectrum (multivariate analysis) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Well-being spectrum (multivariate analysis).
G/G Published research associates this genotype with typical/baseline likelihood of Well-being spectrum (multivariate analysis) — no copies of the reported risk allele.
Source

Questions about rs17049478

What is rs17049478?

rs17049478 is a single position in the genome, in or near the near FANCL gene. Published research associates it with well-being spectrum (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17049478 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17049478 come from?

GWAS Catalog, Nat Genet 2019, PMID:30643256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Well-being spectrum (multivariate analysis) (rs17049478). MyGeneLog™. https://www.mygenelog.com/variants/rs17049478

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