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Insulin-related traits

SC4MOL · rs17046216

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 927 African American non-diabetic individuals; replicated in 570 West African ancestry non-diabetic individuals.

The effect Each copy of the A allele shifted the measure 0.19 higher (95% confidence interval 0.13-0.25); p = 3 × 10⁻⁸.

How common The A allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 4, band 4q32.3 — in an intron of MSMO1.

What each result means

A/A Two copies of the version the research linked to Insulin-related traits. That is the strongest link of the three results. A link in a study is not a diagnosis.

A/T One copy of the version the research linked to Insulin-related traits. That is a smaller link than two copies.

T/T No copy of the version the research linked to Insulin-related traits. This is the starting point the study compared everyone against.

Source

Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans

Chen G, Bentley A, Adeyemo A, Shriner D, Zhou J, Doumatey A, Huang H, Ramos E, Erdos M, Gerry N, Herbert A, Christman M

and 1 more — show all

Rotimi C

Human molecular genetics · 2012 · PMID 22791750

What people read about alongside this

Blood sugar and insulin1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs17046216

What is rs17046216?

rs17046216 is a single position in the genome, in or near the SC4MOL gene. Published research associates it with insulin-related traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs17046216?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs17046216 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17046216 come from?

GWAS Catalog, Hum Mol Genet 2012, PMID:22791750. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insulin-related traits (rs17046216). MyGeneLog™. https://www.mygenelog.com/variants/rs17046216

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