Who was studied 171,643 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0502 higher (95% confidence interval 0.035-0.066); p = 2 × 10−10.
How common The C allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 12, band 12q23.2 — in an intron of SPIC.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Lymphocyte count — no copies of the reported risk allele.
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lymphocyte count.
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lymphocyte count compared to the general population.
rs17041439 is a single position in the genome, in or near the SPIC gene. Published research associates it with lymphocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17041439 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs17041439 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17041439 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.