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Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.
The effect
Each copy of the A allele shifted the measure 0.02 mmol/L lower (95% confidence interval 0.02-0.02); p = 1 × 10−10.
Where it sits Chromosome 3, band 3p22.3 — in an intron of CMTM6.
What each result means
A/ATwo copies of the version the research linked to Concentration of LDL particles. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Concentration of LDL particles. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Concentration of LDL particles. This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 41044249 · open access
Questions about rs17029617
What is rs17029617?
rs17029617 is a single position in the genome, in or near the CMTM6 gene. Published research associates it with concentration of ldl particles. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17029617 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs17029617 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17029617 come from?
GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 261172312Reads by AI crawlersClaude1ChatGPT0Google · Gemini1Perplexity0Meta AI0Microsoft · Copilot7Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others12Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Concentration of LDL particles (rs17029617). MyGeneLog™. https://www.mygenelog.com/variants/rs17029617