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Asthma

IKZF4 · rs1702877

Where this position leads

Condition: Asthma

rs1702877 Condition: Asthma Asthma Condition rs1702877 rs1702877 IKZF4

What the study found

Who was studied 38,369 European ancestry cases, 411,131 European ancestry controls, 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0663 higher (95% confidence interval 0.051-0.081); p = 3 × 10−18.

Where it sits Chromosome 12, band 12q13.2 — in an intron of IKZF4.

What each result means

C/C No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Asthma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1702877

What is rs1702877?

rs1702877 is a single position in the genome, in or near the IKZF4 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1702877 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs1702877 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1702877 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs1702877). MyGeneLog™. https://www.mygenelog.com/variants/rs1702877

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