Sensitive

Chemotherapy induced time to first peripheral neuropathy in cancer

GRID2 · rs17020773

What the study found

Who was studied 4,900 European ancestry individuals.

The effect Each copy of the C allele carried 1.86 times the odds of Chemotherapy induced time to first peripheral neuropathy in cancer (95% confidence interval 1.5-2.31); p = 2 × 10−8.

How common The C allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 4, band 4q22.2 — in an intron of GRID2.

What each result means

C/C Two copies of the version the research linked to Chemotherapy induced time to first peripheral neuropathy in cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Chemotherapy induced time to first peripheral neuropathy in cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Chemotherapy induced time to first peripheral neuropathy in cancer. This is the starting point the study compared everyone against.
Source

Questions about rs17020773

What is rs17020773?

rs17020773 is a single position in the genome, in or near the GRID2 gene. Published research associates it with chemotherapy induced time to first peripheral neuropathy in cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17020773 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17020773 come from?

GWAS Catalog, Genome medicine 2023, PMID:37344884. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Chemotherapy induced time to first peripheral neuropathy in cancer (rs17020773). MyGeneLog™. https://www.mygenelog.com/variants/rs17020773

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