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Who was studied 1,484 European ancestry cases, 550,680 European ancestry controls.
The effect
Each copy of the T allele carried 1.40 times the odds of Erosive hand osteoarthritis (95% confidence interval 1.28-1.53); p = 8 × 10−14.
How common The T allele had a frequency of about 60% in the people studied.
Where it sits Chromosome 4, band 4q22.1 — between genes, 6.4 kb from HSP90AB3P.
What each result means
C/CNo copy of the version the research linked to Erosive hand osteoarthritis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Erosive hand osteoarthritis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Erosive hand osteoarthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Annals of the rheumatic diseases · 2023 · PMID 36931692 · open access
Questions about rs17013495
What is rs17013495?
rs17013495 is a single position in the genome, in or near the near HSP90AB3P gene. Published research associates it with erosive hand osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17013495 linked to?
On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs17013495 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17013495 come from?
GWAS Catalog, Annals of the rheumatic diseases 2023, PMID:36931692. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Erosive hand osteoarthritis (rs17013495). MyGeneLog™. https://www.mygenelog.com/variants/rs17013495