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Estimated glomerular filtration rate

MYH9 · rs16996674

What the study found

Who was studied 18,319 African American or Afro-Caribbean individuals, 98,641 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.57 lower (95% confidence interval 0.37-0.77); p = 2 × 10−8.

Where it sits Chromosome 22, band 22q12.3 — in an intron of MYH9.

What each result means

C/C No copy of the version the research linked to Estimated glomerular filtration rate. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Estimated glomerular filtration rate. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Estimated glomerular filtration rate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16996674

What is rs16996674?

rs16996674 is a single position in the genome, in or near the MYH9 gene. Published research associates it with estimated glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs16996674 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16996674 come from?

GWAS Catalog, Journal of the American Society of Nephrology : JASN 2023, PMID:37261792. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Estimated glomerular filtration rate (rs16996674). MyGeneLog™. https://www.mygenelog.com/variants/rs16996674

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