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Standard
Monocyte count
near IPMK · rs1698403
0 26192311Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot9Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others11Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
1 / 4
Its strongest genetic-study result is p = 10−10, with 1 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 639,696 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 2 × 10−10.
How common The T allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 10, band 10q21.1 — between genes, 15.4 kb from IPMK.
How common each version is
AT
KoreanKRGDB
A 60.4% · T 39.6%
KoreanKorea4K
A 59.2% · T 40.8%
KoreanKorea1K
A 59.5% · T 40.5%
Japanese ToMMo
A 61.1% · T 38.9%
Vietnamese
A 53.7% · T 46.3%
World gnomAD
A 66.0% · T 34.0%
World TOPMed
A 64.8% · T 35.2%
By ancestry gnomAD
East Asian
A 55.5% · T 44.5%
European (non-Finnish)
A 78.2% · T 21.8%
African / African American
A 38.9% · T 61.1%
South Asian
A 71.4% · T 28.6%
Admixed American (Latino)
A 76.3% · T 23.7%
Middle Eastern
A 75.0% · T 25.0%
Finnish
A 78.1% · T 21.9%
Ashkenazi Jewish
A 77.5% · T 22.4%
The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study. The ancestry rows are gnomAD's own groups (via Ensembl), as the survey defines them, not races.
What each result means
A/ANo copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
0 26192311Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot9Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others11Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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