Sensitive

Non-melanoma skin cancer

FAM49A · rs16982256

Where this position leads

Condition: Sun Sensitivity, Freckling and Skin Cancer Risk

rs16982256 Condition: Sun Sensitivity, Freckling and Skin Cancer Risk Sun Sensitivity, Freckling and Skin… Condition rs16982256 rs16982256 FAM49A

What the study found

Who was studied 5,912 European ancestry cases, 181,740 European ancestry controls.

The effect Each copy of the T allele carried 1.49 times the odds of Non-melanoma skin cancer (95% confidence interval 1.29-1.73); p = 5 × 10−8.

Where it sits Chromosome 2, band 2p24.3 — between genes, 36.6 kb from LOC107985855.

What each result means

C/C No copy of the version the research linked to Non-melanoma skin cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Non-melanoma skin cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Non-melanoma skin cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16982256

What is rs16982256?

rs16982256 is a single position in the genome, in or near the FAM49A gene. Published research associates it with non-melanoma skin cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16982256 linked to?

On MyGeneLog this position is linked to Sun Sensitivity, Freckling and Skin Cancer Risk. The research behind each link, and its sources, are set out on that condition page.

Does having rs16982256 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16982256 come from?

GWAS Catalog, Nat Commun 2018, PMID:29739929. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Non-melanoma skin cancer (rs16982256). MyGeneLog™. https://www.mygenelog.com/variants/rs16982256

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