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Who was studied 342,399 European ancestry individuals, 6,015 African ancestry individuals, 7,338 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0195 lower (95% confidence interval 0.013-0.026); p = 2 × 10−10.
Where it sits Chromosome 15, band 15q25.1 — in an intron of CEMIP.
What each result means
A/ANo copy of the version the research linked to Cystatin C levels. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Cystatin C levels. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Cystatin C levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs16972495
What is rs16972495?
rs16972495 is a single position in the genome, in or near the CEMIP gene. Published research associates it with cystatin c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs16972495 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs16972495 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs16972495 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1112233Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others3Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cystatin C levels (rs16972495). MyGeneLog™. https://www.mygenelog.com/variants/rs16972495