Sensitive

Breast cancer

GAREM1 · rs16963205

Where this position leads

Condition: Breast Cancer

rs16963205 Condition: Breast Cancer Breast Cancer Condition rs16963205 rs16963205 GAREM1

What the study found

Who was studied 18,034 African or African American cases, 22,104 African or African American controls.

The effect Each copy of the T allele carried 1.13 times the odds of Breast cancer (95% confidence interval 1.09-1.17); p = 2 × 10−11.

How common The T allele had a frequency of about 75% in the people studied.

Where it sits Chromosome 18, band 18q12.1 — in an intron of GAREM1.

What each result means

C/C No copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs16963205

What is rs16963205?

rs16963205 is a single position in the genome, in or near the GAREM1 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs16963205 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs16963205 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs16963205 come from?

GWAS Catalog, Nature genetics 2024, PMID:38741014. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer (rs16963205). MyGeneLog™. https://www.mygenelog.com/variants/rs16963205

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